Does warfarin prevent deep venous thrombosis in high-risk patients?

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Does warfarin prevent deep venous thrombosis in high-risk patients?

Please use this identifier to cite or link to this item: http://hdl.handle.net/10355/3059

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Title: Does warfarin prevent deep venous thrombosis in high-risk patients?
Author: Spaulding, Rebecca L.; Chambliss, M. Lee; Mackler, Leslie
Keywords: cancer
length of therapy
immobilized patients
Date: 2004-03
Publisher: Family Physicians Inquiries Network
Citation: Journal of Family Practice, 53(3) 2004: 230+.
Abstract: Warfarin (Coumadin) is effective in preventing deep venous thrombosis (DVT) among patients with a history of DVT. Conventional dosing and longer durations are the most effective, but the ideal length of therapy is unknown (strength of recommendation [SOR]: A, based on large randomized controlled trials and meta-analysis). Warfarin is useful in preventing DVT in patients with cancer, specifically those treated with chemotherapy (SOR: B, based on small randomized controlled trials). Warfarin may be effective in preventing DVT in immobilized patients such as those with trauma, spinal cord injury, or stroke (SOR: B, based on an underpowered randomized controlled trial and uncontrolled studies).
URI: http://hdl.handle.net/10355/3059

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