Do statins reduce the risk of stroke?

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Do statins reduce the risk of stroke?

Please use this identifier to cite or link to this item: http://hdl.handle.net/10355/3067

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Title: Do statins reduce the risk of stroke?
Author: Busch, Naomi; Kelsberg, Gary; Kendall, Susan K.
Keywords: lipid profile
cardiac risk
Date: 2004-07
Publisher: Family Physicians Inquiries Network
Citation: Journal of Family Practice, 53(7) 2004: 575-577.
Abstract: HMG Co-A reductase inhibitors (statins) are effective for primary prevention of ischemic stroke in people who have a history of occlusive artery disease, coronary artery disease, or diabetes without history of cerebrovascular disease (strength of recommendation [SOR]: A, based on 1 randomized controlled trial [RCT]). Statins reduce the risk of ischemic stroke in hypertensive patients with multiple cardiovascular risk factors and nonfasting total cholesterol <250 mg/dL (SOR: A, based on RCT). Statins also reduce the risk of ischemic stroke for patients with coronary disease or equivalents (such as diabetes or peripheral artery disease), including patients who have a normal fasting lipid profile (SOR: A, based on RCT). For patients with ischemic stroke who have coronary disease, statins prevent recurrent ischemic stroke; evidence is conflicting about whether this benefit is proportional to initial cholesterol levels (SOR: A, systematic review). Statins do not prevent hemorrhagic stroke (SOR: A, based on RCTs).
URI: http://hdl.handle.net/10355/3067

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