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    First- or second-generation antihistamines: which are more effective at controlling pruritus?

    Crownover, Brian K.
    Jamieson, Barbara
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    [PDF] FirstSecondGenerationAntihistamines.pdf (51.44Kb)
    Date
    2004
    Format
    Article
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    Abstract
    For urticarial itch, first- and second-generation antihistamines have similar clinical benefit and are superior to placebo (strength of recommendation [SOR]: A, systematic review of randomized trials [RCT]). For itch related to atopic dermatitis, antihistamines are no better than placebo (SOR: B, small RCTs and other studies). Other categories of pruritus are best treated with non-antihistamine agents (SOR: C, based on expert opinion and disease-oriented research).
    URI
    http://hdl.handle.net/10355/3069
    Part of
    Journal of family practice, 53, no. 09 (September 2004): 742-744.
    Rights
    OpenAccess.
    This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License.
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