Other than anticoagulation, what is the best therapy for those with atrial fibrillation?

Abstract

Rate control with long-term anticoagulation is recommended for most patients with atrial fibrillation (strength of recommendation [SOR]: A, based on randomized controlled trials [RCTs]). A rhythm-control strategy provides no survival or quality-of life benefit when compared with rate control and causes more adverse drug effects and increased hospitalizations (SOR: A, based on RCTs).