What is the best macrolide for atypical pneumonia?
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Erythromycin, clarithromycin, and azithromycin are equally effective in treating pneumonia caused by Mycoplasma pneumoniae or Chlamydophila (formerly Chlamydia) pneumoniae (strength of recommendation [SOR]: B, small head-to-head trials). Macrolide choice can be based on other considerations--cost, side effects, and effectiveness against other suspected pathogens (SOR: C, expert opinion).
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