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dc.contributor.authorHansen, Lauraeng
dc.contributor.authorHavemann, Jameseng
dc.contributor.authorBurroughs, Marthaeng
dc.date.issued2004eng
dc.description.abstractThe annual rate of decline in forced expiratory volume for 1 second (FEV1) has been researchers' gold standard as an objective measure for progression of chronic obstructive pulmonary disease (COPD). Inhaled corticosteroids (ICS) do not consistently have a statistically significant impact on FEV1 decline, and thus on the progression of COPD (strength of recommendation [SOR]: B, 2 conflicting meta-analyses and numerous conflicting randomized controlled trials). In those studies that did show improvements in FEV1 decline, the change does not appear to be clinically significant (7.7 to 9.0 mL/year). These findings do not take into account the potential impact of ICS on such patient oriented outcomes as exacerbation rates, quality of life, outpatient visits, hospitalization, and mortality.eng
dc.identifier.urihttp://hdl.handle.net/10355/3211eng
dc.languageEnglisheng
dc.publisherFamily Physicians Inquiries Networkeng
dc.relation.ispartofcollectionClinical Inquiries, 2004 (MU)eng
dc.relation.ispartofcommunityUniversity of Missouri--Columbia. School of Medicine. Department of Family and Community Medicine. Family Physicians Inquiries Networkeng
dc.relation.ispartofseriesJournal of family practice, 53, no. 10 (October 2004): 835-836.eng
dc.rightsOpenAccess.eng
dc.rights.licenseThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License.eng
dc.subjectexacerbation frequencyeng
dc.subjectdiseasemoderating therapyeng
dc.subjectforced expiratory volumeeng
dc.subject.lcshLungs Diseases, Obstructiveeng
dc.subject.lcshsteroid drugseng
dc.subject.lcshAdrenocortical hormoneseng
dc.subject.lcshPulmonary function testseng
dc.titleWhat effect do inhaled steroids have on delaying the progression of COPD?eng
dc.typeArticleeng


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