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    What is the most effective diagnostic evaluation of streptococcal pharyngitis?

    Merrill, Barth
    Kelsberg, Gary
    Jankowski, Terry Ann, 1951-
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    [PDF] WhatMostEffectiveDiagnosticPharyngitis.pdf (83.71Kb)
    Date
    2004
    Format
    Article
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    Abstract
    Standardized clinical decision rules, such as the Centor criteria, can identify patients with low likelihood of group A beta-hemolytic streptococ-cal (GABHS) pharyngitis who require no further evaluation or antibiotics (strength of recommendation [SOR]: A, based on validated cohort studies). For patients at intermediate and higher risk by clinical prediction rules, a positive rapid anti-gen detection (RAD) test is highly specific for GABHS (SOR: A, based on systematic reviews of diagnostic trials). A negative RAD test result, using the best technique, approaches the sensitivity of throat culture (SOR: B, based on retrospective cohort studies). In children and populations with an increased prevalence of GABHS and GABHS complications, adding a backup throat culture reduces the risk of missing GABHS due to false-negative RAD results (SOR: C, based on expert opinion).
    URI
    http://hdl.handle.net/10355/3212
    Part of
    Journal of family practice, 53, no. 09 (September 2004): 734+.
    Rights
    OpenAccess.
    This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License.
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    • Clinical Inquiries, 2004

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