What is the most effective diagnostic evaluation of streptococcal pharyngitis?

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What is the most effective diagnostic evaluation of streptococcal pharyngitis?

Please use this identifier to cite or link to this item: http://hdl.handle.net/10355/3212

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Title: What is the most effective diagnostic evaluation of streptococcal pharyngitis?
Author: Merrill, Barth; Kelsberg, Gary; Jankowski, Terry Ann, 1951-
Keywords: positive rapid anti-gen detection test
Centor criteria
throat culture
symptom relief
Date: 2004-09
Publisher: Family Physicians Inquiries Network
Citation: Journal of Family Practice, 53(9) 2004: 734+.
Abstract: Standardized clinical decision rules, such as the Centor criteria, can identify patients with low likelihood of group A beta-hemolytic streptococ-cal (GABHS) pharyngitis who require no further evaluation or antibiotics (strength of recommendation [SOR]: A, based on validated cohort studies). For patients at intermediate and higher risk by clinical prediction rules, a positive rapid anti-gen detection (RAD) test is highly specific for GABHS (SOR: A, based on systematic reviews of diagnostic trials). A negative RAD test result, using the best technique, approaches the sensitivity of throat culture (SOR: B, based on retrospective cohort studies). In children and populations with an increased prevalence of GABHS and GABHS complications, adding a backup throat culture reduces the risk of missing GABHS due to false-negative RAD results (SOR: C, based on expert opinion).
URI: http://hdl.handle.net/10355/3212

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