When should patients with stroke receive thrombolytics?

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When should patients with stroke receive thrombolytics?

Please use this identifier to cite or link to this item: http://hdl.handle.net/10355/3216

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Title: When should patients with stroke receive thrombolytics?
Author: Adair, Gina; Grant, Joel; Pandhi, Nancy; Saunders, Robert; Sadowsky, Iris; West, Brian; Kerns, J. William; Knight, Karen
Keywords: recombinant tissue plasminogen activator (rtPA)
treatment protocol
morbidity
Date: 2004-08
Publisher: Family Physicians Inquiries Network
Citation: Journal of Family Practice, 53(8) 2004: 656+.
Abstract: Thrombolytic therapy should be limited to patients with acute ischemic stroke who meet strict inclusion and exclusion criteria and who can adhere to strict treatment protocol. Patients treated under these conditions have improved combined mortality and disability outcomes at 1 year when treated with recombinant tissue plasminogen activator (rtPA) (number needed to treat [NNT]=18; 95% confidence interval [CI], 11-56) (strength of recommendation [SOR]: B, meta-analysis of randomized controlled trials with significant heterogeneity).
URI: http://hdl.handle.net/10355/3216

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