dc.contributor.author | Werner, Matt | eng |
dc.contributor.author | Kelsberg, Gary | eng |
dc.contributor.author | Weismantel, Arlene McFarlin | eng |
dc.date.issued | 2004 | eng |
dc.description.abstract | In adults with no history of cardiovascular disease, aspirin reduces the risk of nonfatal myocardial infarction (MI). Aspirin prophylaxis does not decrease all-cause mortality, risk of fatal coronary heart disease, or risk of first stroke (strength of recommendation [SOR]: A-, based on multiple randomized controlled trials). The benefits of aspirin use must be weighed against its potential risks, primarily gastrointestinal bleeding and cerebral hemorrhage. The benefit of aspirin increases with higher levels of cardiovascular risk, while the potential for harm remains relatively constant. Adults with a calculated 5-year coronary heart disease (CHD) event risk of 3% or greater should receive prophylaxis (SOR: A, based on multiple randomized controlled trials). The ideal dose of aspirin for prophylaxis is unknown, but it appears that low doses (75-81 mg/d) are as effective as higher doses. | eng |
dc.identifier.uri | http://hdl.handle.net/10355/3219 | eng |
dc.language | English | eng |
dc.publisher | Family Physicians Inquiries Network | eng |
dc.relation.ispartofcollection | Clinical Inquiries, 2004 (MU) | eng |
dc.relation.ispartofcommunity | University of Missouri--Columbia. School of Medicine. Department of Family and Community Medicine. Family Physicians Inquiries Network | eng |
dc.relation.ispartofseries | Journal of family practice, 53, no. 02 (February 2004) | eng |
dc.rights | OpenAccess. | eng |
dc.rights.license | This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License. | eng |
dc.subject | side effects | eng |
dc.subject | myocardial infarction | eng |
dc.subject | dosage | eng |
dc.subject | stroke | eng |
dc.subject.lcsh | Aspirin -- Therapeutic use | eng |
dc.subject.lcsh | Aspirin -- Side effects | eng |
dc.subject.lcsh | Myocardial infarction | eng |
dc.subject.lcsh | Coronary heart disease | eng |
dc.subject.lcsh | Cerebrovascular disease | eng |
dc.title | Which healthy adults should take aspirin? | eng |
dc.type | Article | eng |