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dc.contributor.authorFotinos, Charissaeng
dc.contributor.authorNashelsky, Joaneng
dc.date.issued2005eng
dc.description.abstractIn patients with congestive heart failure due to systolic dysfunction who are in normal sinus rhythm, digoxin therapy reduces rates of hospitalization, as well as clinical deterioration, defined as worsening New York Heart Association (NYHA) classification or an increase in clinical signs and symptoms (strength of recommendation [SOR]: A, systematic review of randomized controlled trials [RCT]). These benefits appear to be more pronounced for men. Patients treated with digoxin are at increased risk of developing supraventricular dysrhythmias and second- or third-degree atrioventricular block (SOR: A, large RCT). It is unclear if patients with diastolic dysfunction experience similar benefits or harms (SOR: A, systematic review of RCTs). Digoxin has not been shown to have any effect on mortality for men with congestive heart failure in sinus rhythm (SOR: A, systematic review of RCTs). Digoxin use for women may be associated with an increased risk of mortality (SOR: B, extrapolation from RCT).eng
dc.identifier.urihttp://hdl.handle.net/10355/3262eng
dc.languageEnglisheng
dc.publisherFamily Physicians Inquiries Networkeng
dc.relation.ispartofcollectionClinical Inquiries, 2005 (MU)eng
dc.relation.ispartofcommunityUniversity of Missouri--Columbia. School of Medicine. Department of Family and Community Medicine. Family Physicians Inquiries Networkeng
dc.relation.ispartofseriesJournal of family practice, 54, no. 06 (June 2005): 556-557eng
dc.rightsOpenAccess.eng
dc.rights.licenseThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License.eng
dc.subjectmortalityeng
dc.subjectsystolic dysfunctioneng
dc.subjectatrioventricular blockeng
dc.subjectsupraventricular dysrhythmiaseng
dc.subject.lcshHeart failureeng
dc.subject.lcshCardiac pacingeng
dc.subject.lcshDigoxineng
dc.subject.lcshCongestive heart failureeng
dc.titleDoes digoxin decrease morbidity for those in sinus rhythm with heart failure?eng
dc.typeArticleeng


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