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dc.contributor.authorAndy, Camilleeng
dc.contributor.authorFlake, Donnaeng
dc.date.issued2005-02eng
dc.description.abstractShort-term use of metformin (Glucophage) improves ovulation rates for women with polycystic ovary syndrome (PCOS) (strength of recommendation [SOR]: A, based on systematic reviews of randomized controlled trials [RCT]). Metformin also decreases menstrual irregularities (SOR: B, extrapolated from a systematic review). When added to clomiphene, metformin increases ovulation and pregnancy rates when compared with clomiphene alone (SOR: A, systematic review). Thiazolidinediones (TZDs) improve ovulation rates as well (SOR: B, based on low-quality RCTs). Research of longer duration including the key outcomes of pregnancy and birth rates, is needed to clarify the appropriate use of insulin-sensitizing drugs for PCOS.eng
dc.identifier.citationJournal of Family Practice, 54(2) 2005: 156+.eng
dc.identifier.urihttp://hdl.handle.net/10355/3285eng
dc.languageEnglisheng
dc.publisherFamily Physicians Inquiries Networkeng
dc.relation.ispartofClinical Inquiries, 2005 (MU)eng
dc.relation.ispartofcommunityUniversity of Missouri-Columbia. School of Medicine. Department of Family and Community Medicine. Family Physicians Inquiries Networkeng
dc.rightsOpenAccess.eng
dc.rights.licenseThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License.eng
dc.subjectbirth rateeng
dc.subjectpolycystic ovary syndromeeng
dc.subjectpregnancy rateeng
dc.subjectmenstruationeng
dc.subject.lcshPolycystic Ovary Syndromeeng
dc.subject.meshThiazolidinediones -- therapeutic useeng
dc.titleDo insulin-sensitizing drugs increase ovulation rates for women with PCOS?eng
dc.typeArticleeng


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