Shared more. Cited more. Safe forever.
    • advanced search
    • submit works
    • about
    • help
    • contact us
    • login
    View Item 
    •   MOspace Home
    • University of Missouri-Columbia
    • Graduate School - Theses and Dissertations (MU)
    • Theses and Dissertations (MU)
    • Theses (MU)
    • 2012 Theses (MU)
    • 2012 MU theses - Freely available online
    • View Item
    •   MOspace Home
    • University of Missouri-Columbia
    • Graduate School - Theses and Dissertations (MU)
    • Theses and Dissertations (MU)
    • Theses (MU)
    • 2012 Theses (MU)
    • 2012 MU theses - Freely available online
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.
    advanced searchsubmit worksabouthelpcontact us

    Browse

    All of MOspaceCommunities & CollectionsDate IssuedAuthor/ContributorTitleSubjectIdentifierThesis DepartmentThesis AdvisorThesis SemesterThis CollectionDate IssuedAuthor/ContributorTitleSubjectIdentifierThesis DepartmentThesis AdvisorThesis Semester

    Statistics

    Most Popular ItemsStatistics by CountryMost Popular AuthorsStatistics by Referrer

    Parenteral fish oil effects on plasma non-esterified fatty acids and systemic cytokine concentrations in dogs immediately following ovariohysterectomy

    Tsuruta, Kaoru
    View/Open
    [PDF] public. pdf.pdf (48.92Kb)
    [PDF] research. pdf.pdf (721.1Kb)
    [PDF] short.pdf (11.76Kb)
    Date
    2012
    Format
    Thesis
    Metadata
    [+] Show full item record
    Abstract
    An extreme systemic inflammatory response may be observed in dogs that experience severe accidental trauma, such as being struck by a car. The inflammatory response may be so extreme that it complicates treatment and causes multiple organ failure. There are few currently available methods to counter an extreme systemic inflammatory response. The aim of this project was to use an ovariohysterectomy model to determine if systemic inflammatory mediators released in response to controlled trauma can be modulated by a fish oil infusion high in omega-3 fatty acids. Three different cephalic vein infusates (fish oil, soybean oil, or saline) were given to dogs immediately following ovariohysterectomy and cytokine concentrations in jugular venous plasma samples were compared. After fish oil infusion, plasma omega-3 fatty acid concentration markedly increased, but the increased concentration was not long-lasting. Cytokine production when stimulated by pathogen-associated molecular patterns was increased by trauma (ovariohysterectomy), but it was not suppressed by fish oil infusion. Assuming cytokine production by circulating leukocytes is a marker of systemic inflammation, fish oil emulsion infusion at the dose and duration studied did not appear to attenuate the systemic inflammatory response.
    URI
    http://hdl.handle.net/10355/33166
    Degree
    M.S.
    Thesis Department
    Veterinary biomedical sciences (MU)
    Rights
    OpenAccess.
    This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License.
    Collections
    • 2012 MU theses - Freely available online
    • Biomedical Sciences electronic theses and dissertations (MU)

    Send Feedback
    hosted by University of Missouri Library Systems
     

     


    Send Feedback
    hosted by University of Missouri Library Systems