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    What are effective therapies for Clostridium difficile- associated diarrhea?

    Ohl, Michael E.
    Stevermer, James J.
    Meadows, Susan E.
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    [PDF] WhatEffectiveTherapiesDiarrhea.pdf (86.87Kb)
    Date
    2005
    Format
    Article
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    Abstract
    Oral metronidazole and oral vancomycin are equally effective treatments for Clostridium difficile- associated diarrhea (CDAD) (strength of recommendation [SOR]: A, based on randomized trials). Oral vancomycin is considerably more expensive and may select for colonization with vancomycin-resistant enterococci, leading the American College of Gastroenterology to recommend oral metronidazole as preferred therapy (SOR: C, expert opinion). They recommend therapy with vancomycin for those who are pregnant, breast feeding, less than 10years old, nonresponders to metronidazole, critically ill, or allergic or intolerant to metronidazole (SOR: C, expert opinion).
    URI
    http://hdl.handle.net/10355/3349
    Part of
    Journal of family practice, 54, no. 02 (February 2005): 176-178.
    Rights
    OpenAccess.
    This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License.
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    • Clinical Inquiries, 2005

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