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    What is the role of tacrolimus and pimecrolimus in atopic dermatitis?

    Trammell, Sara
    Shakil, Amer
    Wilder, Laura
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    [PDF] WhatRoleTacrolimus.pdf (69.61Kb)
    Date
    2005
    Format
    Article
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    Abstract
    When the standard therapies -- mild topical corticosteroids and moisturizers -- fail in the treatment of atopic dermatitis, patients are left with few proven remedies. The recently introduced topical immunosuppressive treatment --pimecrolimus and tacrolimus -- offer an alternative to topical corticosteroids. Tacrolimus 0.1% (Protopic) appears to be both safe and effective in treating eczema in adults and children (strength of recommendation [SOR]: A). In multiple studies, it has been as effective as potent topical corticosteroids and more effective than mild topical corticosteroids (SOR: A). Pimecrolimus (Elidel) is more effective than placebo but less effective than potent topical corticosteroids (SOR: A). At this time, no data compare pimecrolimus with mild corticosteroids.
    URI
    http://hdl.handle.net/10355/3381
    Part of
    Journal of family practice, 54, no. 08 (August 2005)
    Rights
    OpenAccess.
    This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License.
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