• How should you manage a depressed patient unresponsive to an SSRI? 

    Triezenberg, Daniel; Vachon, Dominic; Helmen, Jennifer (Family Physicians Inquiries Network, 2006-12)
    The best approach among studied alternatives to manage a patient with treatment-resistant depression is not clear from the evidence. All of the options reviewed seem to have about a 25% to 30% success rate. Switching to ...