Which patients undergoing colonoscopy should have spontaneous bacterial endocarditis (SBE) prophylaxis?
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Routine administration of prophylactic antibiotics to prevent infective endocarditis (IE) from colonoscopy is not recommended. It is reasonable to give prophylactic treatment to patients with a known gastrointestinal (GI) tract infection as well as a prosthetic heart valve, valve repair with prosthetic material, or previous IE, cardiac transplant patients with subsequent valvulopathy, and some patients with congenital heart disease (SOR: C, consensus guidelines).
Evidence Based Practice 16(3): 08.