Should people with a first-degree relative who died from subarachnoid hemorrhage be screened for aneurysms?

Abstract

Patients whose family history includes 1 first-degree relative with subarachnoid hemorrhage caused by intracranial aneurysm (ICA) need not be screened for ICAs (strength of recommendation [SOR]: B, based on a single case series). Hypertension, hyperlipidemia, ethanol use, and tobacco use do not increase the risk of ICA for patients whose primary family member had an ICA (SOR: B, based on case series). Screening for intracranial aneurysms is not cost-effective (SOR: C, mathematical modeling/expert opinion).