Cockroft-Gault formula vs modification diet in renal disease formula for calculating renal function in older adults
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In hospitalized patients older than 70 years, the Cockroft-Gault (CG) formula generates an estimate of creatinine clearance (CrCl) that is closer to the measured 24-hour creatinine than the modification diet in renal disease (MDRD) formula. The CG tends to slightly underestimate the CrCl, while the MDRD tends to overestimate it.
Evidence Based Practice 16(6): 05.