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    What is the best way to manage GERD symptoms in the elderly?

    Bacak, Brian S.
    Patel, Mihir
    Tweed, Elizabeth M.
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    [PDF] WhatWayManageGERD.pdf (134.9Kb)
    Date
    2006
    Format
    Article
    Metadata
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    Abstract
    No evidence supports one method over another in managing uncomplicated gastroesophageal reflux disease (GERD) for patients aged >65 years. For those with endoscopically documented esophagitis, proton pump inhibitors (PPIs) relieve symptoms faster than histamine H2 receptor antagonists (H2RAs) (strength of recommendation [SOR]: B, extrapolation from randomized controlled trials [RCTs]). Treating elderly patients with pantoprazole (Protonix) after resolution of acute esophagitis results in fewer relapses than with placebo (SOR: B, double-blind RCT). Limited evidence suggests that such maintenance therapy for prior esophagitis with either H2RAs or PPIs, at half- and full-dose strength, decreases the frequency of relapse (SOR: B, extrapolation from uncontrolled clinical trial).
    URI
    http://hdl.handle.net/10355/3581
    Part of
    Journal of family practice, 55, no. 03 (March 2006)
    Rights
    OpenAccess.
    This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License.
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    • Clinical Inquiries, 2006

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