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    Which medications can be split without compromising efficacy and safety?

    Noviasky, John
    Lo, Vincent
    Luft, Diane Davis
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    [PDF] WhichMedicationsCanBeSplit.pdf (65.79Kb)
    Date
    2006
    Format
    Article
    Metadata
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    Abstract
    Split tablets of lisinopril are as effective as whole tablets of the same dose for hypertension (SOR: B, based on small randomized crossover study). Similarly, split tablets of atorvastatin, lovastatin, and simvastatin are no less effective for lowering cholesterol (SOR: B, based on retrospective cohort studies). Extended-release, entericcoated, or tablets that cannot be split accurately are not appropriate for splitting (SOR: C, based on observational studies); the accuracy of splitting also depends on device used and user skill (SOR: C, based on observational study).
    URI
    http://hdl.handle.net/10355/3588
    Part of
    Journal of family practice, 55, no. 08 (August 2006): 707-708
    Rights
    OpenAccess.
    This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License.
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