Are there big differences among beta-blockers in treating essential hypertension?

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Are there big differences among beta-blockers in treating essential hypertension?

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Title: Are there big differences among beta-blockers in treating essential hypertension?
Author: Sontheimer, Daniel; Hitchcock, Kristin
Keywords: lung function
adverse outcomes
fatigue
Date: 2007-04
Publisher: Family Physicians Inquiries Network
Citation: Journal of Family Practice, 56(4) 2007: 312-314.
Abstract: Yes, a number of beta-blockers are effective in lowering blood pressure (strength of recommendation [SOR]: A, multiple, consistent randomized controlled trials [RCTs]). Cardioselective beta-blockers do not alter lung function studies for patients with chronic obstructive pulmonary disease (COP D) or reversible airway disease (SOR: A, meta-analysis of RCTs). Propranolol and timolol have greater risks of causing fatigue as a side effect (SOR: A, meta- analysis of RCTs). Recent meta-analyses have stirred debate on the effectiveness of the agents in preventing adverse outcomes. The level of evidence has reached the point where the practice of using beta-blockers as monotherapy should be questioned (SOR : C, expert opinion).
URI: http://hdl.handle.net/10355/3599

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