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    Are there big differences among beta-blockers in treating essential hypertension?

    Sontheimer, Daniel
    Hitchcock, Kristin
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    [PDF] AreThereBigDifferences.pdf (91.37Kb)
    Date
    2007
    Format
    Article
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    Abstract
    Yes, a number of beta-blockers are effective in lowering blood pressure (strength of recommendation [SOR]: A, multiple, consistent randomized controlled trials [RCTs]). Cardioselective beta-blockers do not alter lung function studies for patients with chronic obstructive pulmonary disease (COP D) or reversible airway disease (SOR: A, meta-analysis of RCTs). Propranolol and timolol have greater risks of causing fatigue as a side effect (SOR: A, meta- analysis of RCTs). Recent meta-analyses have stirred debate on the effectiveness of the agents in preventing adverse outcomes. The level of evidence has reached the point where the practice of using beta-blockers as monotherapy should be questioned (SOR : C, expert opinion).
    URI
    http://hdl.handle.net/10355/3599
    Part of
    Journal of family practice, 56, no. 04 (April 2007): 312-314
    Rights
    OpenAccess.
    This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License.
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    • Clinical Inquiries, 2007

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