Can you differentiate bacterial from viral pediatric infections based on the CBC?
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No—the complete blood count (CBC) alone does not have adequate sensitivity or specificity to tell bacterial from viral infections (strength of recommendation [SOR]: B, cohort studies). When used in conjunction with other clinical parameters in validated decision-making algorithms, the CBC can help detect serious bacterial infections in pediatric patients with fever (SOR: B, cohort studies).
Journal of Family Practice, 56(5) 2007: 390-392.