What is the differential diagnosis for extremely elevated (5?? normal) alkaline phosphatase?
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In patients with very high alkaline phosphatase levels (>1,000 IU/L), the differential diagnosis includes sepsis, malignant obstruction within the hepatic system, liver metastasis, infiltrative liver disease, and AIDS (SOR: C, case series).
Evidence-based practice 16, no. 07 (2013): 10-11