What GI stress ulcer prophylaxis should we provide hospitalized patients?

Abstract

Patients in intensive care unit (ICE) settings who are receiving prolonged mechanical ventilation (for >48 hours) or who have a coagulopathy or multiple organ dysfunction (especially renal failure) should receive stress ulcer prophylaxis. Current evidence does not support prophylaxis for non-ICU patients(strength of recommendation [SOR]: B, based on multiple systematic reviews).