What's the best treatment for cradle cap?
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Ketoconazole (Nizoral) shampoo appears to be a safe and efficacious treatment for infants with cradle cap (strength of recommendation [SOR]: C, consensus, usual practice, opinion, disease-oriented evidence, and case series). Limit topical corticosteroids to severe cases because of possible systemic absorption (SOR: C). Overnight application of emollients followed by gentle brushing and washing with baby shampoo helps to remove the scale associated with cradle cap (SOR: C).
Journal of Family Practice, 56(3) 2007: 232-233.