Leukotriene Receptor Antagonists for the Treatment of Allergic Skin Disorders

Abstract

Evidence from small trials suggests that leukotriene receptor antagonists may have short-term effectiveness in reducing sleep disturbance and the observed intensity of atopic dermatitis in adults and children. (Strength of Recommendation [SOR]: B, based on small randomized controlled trials [RCTs] and case series). There are inconsistent results regarding the effectiveness of leukotriene receptor antagonists for treatment of chronic idiopathic urticaria when used alone or in combination with antihistamines (SOR: B, based on meta- analysis of small, limited trials).