What's the most effective treatment for giardiasis?
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A single 2-g dose of tinidazole is the best treatment (strength of recommendation [SOR]: A, based on meta-analysis). Other drugs, such as nitazoxanide, metronidazole, mebendazole, and albendazole, can also be used (SOR: A, based on randomized controlled trial [RCT] of patient-oriented outcomes), but tinidazole has a higher clinical cure rate than these drugs. It also has a comparable side-effect profile and requires only 1 dose.
Journal of Family Practice, 57(4) 2008: 270+.