What is the most effective and safe malaria prophylaxis during pregnancy?
Abstract
Chloroquine and mefloquine have superior
safety profiles in pregnancy, though all
antimalarials are effective for prophylaxis.
Antimalarials will decrease the severity of
maternal malaria infection and malaria-associated anemia, while decreasing the
incidence of low birth weight and perinatal
death in women having their first or
second baby (strength of recommendation
[SOR]: A, based on systematic review of
consistent, good-quality patient-oriented
evidence).
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