What is the best way to eradicate the staph carrier state in a patient with recurrent staph skin infections?
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In patients who are nasal carriers, intranasal mupirocin effectively eradicates intranasal Staphylococcus aureus with a 90% success rate at 1 week (SOR: A, meta-analysis). The addition of bleach baths to nasal mupirocin promotes longer term eradication in patients with colonization beyond the nose (SOR: B, RCT).
Evidence Based Practice 16(9): 09-10.