How common is uterine tachysystole with fetal heart rate abnormalities when inducing labor with misoprostol?
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The rate of uterine tachysystole with fetal heart rate (FHR) abnormalities is dependent on the route and dose of misoprostol administration and is probably between 0% and 13%. Less tachysystole is seen with oral misoprostol than vaginal preparations. Lower doses of vaginal misoprostol are better tolerated than higher doses (SOR: A, systematic reviews).
Evidence Based Practice 16(9): 14.