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dc.contributor.authorChilakamarri, Geethaeng
dc.contributor.authorWeismantel, Davideng
dc.contributor.authorWeismantel, Arlene McFarlineng
dc.date.issued2009eng
dc.description.abstractlithium, triiodothyronine (T3), and atypical antipsychotics are all effective adjuncts. Lithium (serum levels >0.5 mEq/L) can produce clinical improvement when added to ineffective antidepressant treatment (strength of recommendation [SOR]: A, meta-analysis of randomized controlled trials [RCTs]). Thyroid supplementation using T3 at doses no higher than 50 mcg per day also increases the effectiveness of antidepressant therapy (SOR: B, meta- analysis of RCT and cohort studies). Atypical antipsychotic agents are less effective adjuncts for patients with treatment-resistant major depressive disorder (SOR: B, meta-analysis of RCT and cohort studies).eng
dc.identifier.urihttp://hdl.handle.net/10355/3862eng
dc.languageEnglisheng
dc.publisherFamily Physicians Inquiries Networkeng
dc.relation.ispartofcollectionClinical Inquiries, 2009 (MU)eng
dc.relation.ispartofcommunityUniversity of Missouri-Columbia. School of Medicine. Department of Family and Community Medicine. Family Physicians Inquiries Networkeng
dc.relation.ispartofseriesJournal of family practice, 58, no. 10 (October 2009): 550-551.eng
dc.rightsOpenAccess.eng
dc.rights.licenseThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License.eng
dc.subjectthyroid supplementationeng
dc.subjectSequenced Treatment Alternatives to Relieve Depression (STAR*D)eng
dc.subjectatypical antipsychotic agentseng
dc.subject.lcshAntidepressantseng
dc.subject.lcshAntipsychotic drugseng
dc.subject.lcshLithium -- Therapeutic useeng
dc.subject.lcshTriiodothyronine -- Therapeutic useeng
dc.titleCan nonantidepressants help treat depression?eng
dc.typeArticleeng


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