Treatment of Otitis Media with Perforated Tympanic Membrane
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Acute otitis media with tympanic membrane perforation in children should be treated with an oral antibiotic. (Strength of Recommendation [SOR]: A, based on meta- analysis of randomized controlled trials [RCTs]). Topical ciprofloxacin/dexamethasone (Ciprodex) is better than oral amoxicillin/ clavulanic acid (Augmentin) for treating acute otitis media in children with tympanostomy tubes. (SOR: B, based on a small RCT). Topical quinolone antibiotics, with or without topical corticosteroids, are the best treatment for chronic suppurative otitis media. (SOR: A, based on systematic reviews of RCTs).
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