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dc.contributor.authorAbdel Badaee, Hodaeng
dc.contributor.authorEdrees, Amreng
dc.contributor.authorAmin, Sherifeng
dc.contributor.authorEl Amir, Mahereng
dc.contributor.authorRagab, Gaafareng
dc.date.issued2013-09-02eng
dc.description.abstractAbstract Behcet’s disease is a chronic multi-system disorder of unknown etiology with protean manifestations. Venous thromboembolism is more common than arterial thrombosis, with deep vein thrombosis being the most frequent. Endothelial dysfunction resulting from vascular inflammation is considered to be an important factor of thrombosis, although the endothelial injury itself cannot completely explain the hypercoagulable state of the disease because other vasculitis syndromes do not increase the risk of thrombosis. The aim of this study is to evaluate the prevalence of activated protein C resistance (APC-R) in Egyptian patients with Behcet’s disease. Also, to detect hyperhomocysteinemia in selected cases (with vascular complications) to assess their relationship with thromboembolic complications. The APC resistance ratio mean in the group of patients with vascular involvement was 2.6 ± 0.8 which was less than the group with no vascular involvement 2.8 ± 0.6, with non- significant P-value (0.5). There was more incidence of ocular lesions in the group of patients with high homocysteine level than the group of patients with normal homocytsteine level with significant P-value (0.08).eng
dc.description.versionPeer Reviewedeng
dc.identifier.citationThrombosis Journal. 2013 Sep 02;11(1):17eng
dc.identifier.urihttp://dx.doi.org/10.1186/1477-9560-11-17eng
dc.identifier.urihttp://hdl.handle.net/10355/38977eng
dc.rights.holderHoda Abdel Badaee et al.; licensee BioMed Central Ltd.eng
dc.titleActivated protein C resistance in Behcet's diseaseeng
dc.typeJournal Articleeng


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