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    What Is the Best Antiviral Agent for Influenza Infection?

    Fagan, Heather Bittner
    Moeller, Amy Hollihan
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    [PDF] WhatAntiviralAgentInfluenza.pdf (40.86Kb)
    Date
    2004
    Format
    Article
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    Abstract
    Four antiviral agents have been approved by the U.S. Food and Drug Administration for the treatment of influenza infection: amantadine (Symmetrel), oseltamivir (Tamiflu), rimantadine (Flumadine), and zanamivir (Relenza). No head-to-head trials have compared the effectiveness of these agents, and no direct evidence exists regarding their relative efficacy. In the absence of specific contraindications, amantadine and rimantadine are preferred for use in most patients because these two agents cost less than the other two. Patients with renal insufficiency or a seizure disorder should not take amantadine, and patients with chronic obstructive pulmonary disease or asthma should not take zanamivir. [Strength of recommendation: C]
    URI
    http://hdl.handle.net/10355/3929
    Part of
    American family physician, 70, no. 07 (October 2004)
    Rights
    OpenAccess.
    This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License.
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    • Clinical Inquiries, 2004

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