Risks and Benefits of Combination Contraceptives
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The risks of using oral combination contraceptives include: a three- to sixfold increase in the incidence of venous thromboembolism (VTE) apparent by the fourth month of use and highest between six and 12 months of use; a two- to sixfold increase in the risk of ischemic stroke among women with a history of migraine; and an increase in cervical cancer risk after five or more years of use. (Strength of Recommendation [SOR]: B)
American Family Physician, 74(11) 2006.
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