Metformin Therapy and Diabetes Prevention in Adolescents Who Are Obese

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Metformin Therapy and Diabetes Prevention in Adolescents Who Are Obese

Please use this identifier to cite or link to this item: http://hdl.handle.net/10355/3978

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Title: Metformin Therapy and Diabetes Prevention in Adolescents Who Are Obese
Author: Rodriguez, Jose E.; Shearer, Barbara
Keywords: obesity
type 2 diabetes
lifestyle modification
polycystic ovary syndrome
Date: 2007-11
Publisher: Family Physicians Inquiries Network
Citation: American Family Physician, 76(9) 2007.
Abstract: No studies have addressed the question of whether metformin reduces development of diabetes among adolescents who are obese. Metformin treatment in adolescents who are obese can modestly reduce risk factors for type 2 diabetes, including elevated body mass index (BMI), fasting insulin levels, and fasting glucose levels. (Strength of Recommendation [SOR]: C). However, metformin treatment is associated with nausea, abdominal pain, and diarrhea. (SOR: A). Because of the limited available data, metformin is not recommended for diabetes prevention in adolescents. (SOR: C).
URI: http://hdl.handle.net/10355/3978

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