dc.contributor.author | Rodriguez, Jose E. | eng |
dc.contributor.author | Shearer, Barbara | eng |
dc.date.issued | 2007 | eng |
dc.description.abstract | No studies have addressed the question of whether metformin reduces development of diabetes among adolescents who are obese. Metformin treatment in adolescents who are obese can modestly reduce risk factors for type 2 diabetes, including elevated body mass index (BMI), fasting insulin levels, and fasting glucose levels. (Strength of Recommendation [SOR]: C). However, metformin treatment is associated with nausea, abdominal pain, and diarrhea. (SOR: A). Because of the limited available data, metformin is not recommended for diabetes prevention in adolescents. (SOR: C). | eng |
dc.identifier.uri | http://hdl.handle.net/10355/3978 | eng |
dc.language | English | eng |
dc.publisher | Family Physicians Inquiries Network | eng |
dc.relation.ispartofcollection | Clinical Inquiries, 2007 (MU) | eng |
dc.relation.ispartofcommunity | University of Missouri-Columbia. School of Medicine. Department of Family and Community Medicine. Family Physicians Inquiries Network | eng |
dc.relation.ispartofseries | American family physician, 76, no. 09 (November 2007) | eng |
dc.rights | OpenAccess. | eng |
dc.rights.license | This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License. | eng |
dc.subject | obesity | eng |
dc.subject | type 2 diabetes | eng |
dc.subject | lifestyle modification | eng |
dc.subject | polycystic ovary syndrome | eng |
dc.subject.lcsh | Metformin | eng |
dc.subject.lcsh | Obesity in children | eng |
dc.subject.lcsh | Non-insulin-dependent diabetes | eng |
dc.title | Metformin Therapy and Diabetes Prevention in Adolescents Who Are Obese | eng |
dc.type | Article | eng |