Browsing Theses and Dissertations (MU) by Thesis Advisor "Hawthorne, M. Frederick"
Now showing items 1-5 of 5
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Closomers at a click : a treatise on the design, synthesis and in vivo MRI of novel click closomers as high performance and efficacious contrast agents
(University of Missouri--Columbia, 2013)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] The advent of Magnetic Resonance Imaging or MRI has truly revolutionized the field of medical diagnostic and imaging. The signal intensity and the ... -
Design and development of a polyhedral borane drug delivery system for the small-molecule antimetabolite 5-fluorouracil
(University of Missouri--Columbia, 2014)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Polyhedral boranes represent a unique class of molecules that have been exploited for a variety of applications. Their unique bonding provides a novel ... -
Hydrolytic stability of carbamate and carbonate closomers for the design of a multifaceted drug delivery system
(University of Missouri--Columbia, 2011)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Twelve-fold substituted polyhedral boranes (closomers) are of therapeutic and diagnostic interest in the applications of targeted drug delivery. These ... -
Preparation of polymeric boron-containing nanoparticles by emulsion polymerization for application in boron neutron capture therapy (BNCT)
(University of Missouri--Columbia, 2010)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Boron neutron capture therapy (BNCT) is based on the nuclear capture reaction of isotope [superscript 10]B irradiated by low energy thermal neutron ... -
Synthesis of silyloxyacrolein for [4+3] cycloaddition and preparation of carbonate closomer
(University of Missouri--Columbia, 2008)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Followed by Funk's method, I synthesized silyloxyacroleins and used them as dienophiles to react with different dienes in [4+3] cycloaddition reaction. ...