Browsing Theses and Dissertations (MU) by Thesis Advisor "McClellan, Andrew"
Now showing items 1-7 of 7
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Changes in properties of lamprey reticulospinal neurons following spinal cord injury
(University of Missouri--Columbia, 2015)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] The lamprey is one of the most ancient vertebrates, sharing many of basic characteristics of the brain and spinal cord with higher, more evolved ... -
The effects of axotomy on the biophysical properties of reticulospinal neurons in larval lamprey
(University of Missouri--Columbia, 2006)Following severe spinal cord injury (SCI), in adult higher vertebrates there is little or no axonal regeneration, and animals remain paralyzed below the lesion. In contrast, lower vertebrates such as the lamprey, following ... -
Glutamate regulates neurite outgrowth of descending neurons in culture from larval lamprey
(University of Missouri--Columbia, 2005)In spinal cord-transected larval lamprey, descending brain neurons, most of which are reticulospinal (RS) neurons, regenerate their axons across a transection site and contribute to behavioral recovery. In the present ... -
Neuronal changes underlying altered biophysical properties of reticulospinal neurons following spinal cord injury in the lamprey
(University of Missouri--Columbia, 2017)Following a severe spinal cord injury (SCI), the descending axons of reticulospinal (RS) neurons are damaged, resulting in paralysis below the site of the injury. For higher vertebrates, including humans, RS neurons are ... -
Organization of brain and spinal cord locomotor networks in larval lamprey
(University of Missouri--Columbia, 2006)In vertebrates, brain locomotor command systems activate spinal central pattern generators (CPGs) to initiate locomotor behavior. The size and pharmacology of brain command systems are unknown, and the movements that result ... -
Spinal cord injury induces changes in ion channels of reticulospinal neurons in larval lamprey
(University of Missouri--Columbia, 2008)After spinal cord injury in larval lamprey, RS neurons regenerate their axons (Davis and McClellan, 1994a,b), restore synaptic contacts and most of the original locomotor functions (McClellan, 1998). It was previously ... -
Topological organization of the trigeminal system in the lamprey and restoration following axonal regeneration
(University of Missouri--Columbia, 2012)The nervous systems of lower vertebrates, such as the lamprey, share many of the basic features of the brain and spinal cord of higher vertebrates. However, unlike humans and other higher vertebrates, the lamprey displays ...