Browsing Theses (MU) by Thesis Advisor "Daniels, Mark A."
Now showing items 1-2 of 2
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Proposed characterization of POSH function in human T-cell Acute Lymphoblastic Leukemia
(University of Missouri--Columbia, 2023)T-cell Acute Lymphoblastic Leukemia (T-ALL) is an aggressive malignancy that is characterized by leukemic T-cells that can express reduced T-cell markers (such as CD5, CD4, or CD8) reflecting their transformation from an ... -
The roles of ERK pathway localization and the regulation of [beta]-catenin/Bcl-XL kinetic in thymic selection
(University of Missouri--Columbia, 2011)Thymocytes undergo a process of development that serves to favor the differentiation of T-cells bearing self-MHC (major histo-compatibility complex) restricted T-cell receptors (TCR). Signaling through the TCR is crucial ...