Browsing Theses (MU) by Thesis Department "Veterinary biomedical sciences (MU)"
Now showing items 1-20 of 47
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6-Thioguanine and zebularine globally demethylate a canine lyphoma cell line
(University of Missouri--Columbia, 2014)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Epigenetic modifications of chromatin, including methylation, histone modifications, and protein chaperoning, play a significant role in the biology ... -
Analysis of coffin and shoulder joint lameness with an inertial sensor-based system : impact versus pushoff
(University of Missouri--Columbia, 2012)Reason for performing the study: An inertial sensor-based system (Lameness Locator[copyright] [LL]) can help veterinarians detect mild lameness. It would be beneficial if this tool could also be used to distinguish lamenesses ... -
The antiendotoxin effects of polymyxin B in a feline model of endotoxemia
(University of Missouri--Columbia, 2010)Introduction: Directed, effective therapies for feline sepsis are needed to reduce the high morbidity and mortality associated with this disease. Materials and Methods: We investigated the anti-endotoxin effects of PMB in ... -
Canine pharmacodynamic assays: applications in immune-mediated disease
(University of Missouri--Columbia, 2013)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Immune-mediated diseases are commonly diagnosed in veterinary medicine and a high rate of mortality, expense and complications of immunosuppressive ... -
Characterization of the alignment of the canine pelvic limb
(University of Missouri--Columbia, 2009)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Angular limb deformities are common place in the canine. Until recently, repair of deformities was based upon crude radiographic measures of bone ... -
Characterization of the humoral immune response to a commercial staphylococcus aureus mastitis vaccine
(University of Missouri--Columbia, 2006)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] The objective of this thesis was to test the hypothesis that a commercial vaccine for bovine S. aureus mastitis fails to induce a humoral immune response ... -
Comparative imaging of canine shoulder osteochondrosis lesions
(University of Missouri--Columbia, 2010)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Over the last several years, papers have been published describing imaging techniques for the canine shoulder joint using both ultrasound and magnetic ... -
Comparison of an inertial sensor based system of lameness quantification to subjective lameness evaluation
(University of Missouri--Columbia, 2012)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Recently developed wireless inertial sensor systems provide a means to objectively detect lameness as a horse is trotted over natural footing. The ... -
Comparison of left 4th and 5th intercostal space thoracotomy for open-chest cardiopulmonary resuscitation in dogs
(University of Missouri--Columbia, 2018)Open-chest cardiopulmonary resuscitation (OC-CPR) is indicated in certain cardiopulmonary arrest situations such as thoracic trauma. Laboratory research and clinical studies in human medicine have established the superiority ... -
Comprehensive characterization of canine meniscal pathology
(University of Missouri--Columbia, 2010)Meniscal injury is one of the most common causes of pain and dysfunction in the human knee and canine stifle joint. In the canine patient, meniscal injury is usually secondary to cranial cruciate ligament rupture, and the ... -
Cytauxzoon felis : an emerging feline pathogen and potential therapy
(University of Missouri--Columbia, 2011)Cytauxzoon felis is a pathogenic hemoprotozoal parasite of Felidae. We were able to document, via both piroplasm detection and PCR analysis, a chronic carrier state in naturally infected captive bred tigers as well as ... -
Development of a motor unit number estimation technique in normal dogs : a potential biomarker for canine degenerative myelopathy
(University of Missouri--Columbia, 2011)Motor unit number estimation (MUNE) is an electrophysiologic technique for quantifying the lower motor neuron (LMN) system. MUNE has proven useful in evaluating and monitoring neurodegenerative diseases such as amyotrophic ... -
Double pelvic osteotomy for the treatment of hip dysplasia in dogs
(University of Missouri--Columbia, 2011)Canine hip dysplasia (CHD) is the most common developmental orthopedic disease of dogs. Triple pelvic osteotomy (TPO) is a surgery that can be performed at 5 months of age, prior to the development of osteoarthritis. ... -
The effect of free fatty acids on endothelial cells
(University of Missouri--Columbia, 2005)The purpose of this thesis was to determine if specific components of oxidized low density lipoprotein (OxLDL) molecules e.g. oxidized polyunsaturated fatty acids (PUFAs), or saturated free fatty acids (FFA) are alone ... -
Effect of induced hindlimb length difference on bodymounted inertial sensor measures of hindlimb lameness in horses
(University of Missouri--Columbia, 2019)This study has investigated the effect of induced hindlimb length difference on differences in minimum and maximum pelvic heights in horses trotting in a straight line and lungeing on both hard and soft surfaces. The horses ... -
The effect of sodium/hydrogen exchanger inhibition on chemotherapy-induced intestinal epithelial damage
(University of Missouri--Columbia, 2017)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] The small intestinal epithelium is one of the most rapidly dividing tissues in the mammalian body, making it an inadvertent target of non-specific ... -
The effects of furosemide on ureteral diameter and attenuation using computed tomographic excretory urography in normal healthy dogs
(University of Missouri--Columbia, 2012)A number of imaging techniques have been employed to try and diagnose ureteral disease, including ectopic ureters. CTEU has overcome those disadvantages and has become the imaging modality of choice for evaluating human ... -
Effects of voluntary running on brain mitochondrial biogenesis in rats selectively bred to run high and low nightly distances
(University of Missouri--Columbia, 2015)It is known that brain mitochondrial dysfunction is strongly associated with the advent of neurodegenerative diseases and that exercise is an important non-pharmaceutical method of maintaining brain mitochondrial health. ... -
Estradiol regulates multiple tetrodotoxin-sensitive sodium currents in gonadotropin releasing hormone neurons: implications for cellular regulation of reproduction
(University of Missouri--Columbia, 2009)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] The gonadotropin releasing hormone (GnRH) neuron is the pivotal control center in a tightly regulated reproductive axis. Estradiol typically has a ... -
Estrogen receptor [alpha] and [beta] knock-out effects on skeletal muscle in mature female and male mice, and aromatase knock-out effects on skeletal muscle in mature male mice
(University of Missouri--Columbia, 2007)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Estrogen regulates skeletal muscle mass and function in female. Estrogen may influence skeletal muscle mass and function during development in males ...