Browsing Theses (MU) by Thesis Advisor "Weisman, Gary A."
Now showing items 1-5 of 5
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Characterization and functional analysis of the P2Y₂R gene promoter
(University of Missouri--Columbia, 2006)Extracellular nucleotides can bind to the P2Y₂R and modulate proliferation and migration of smooth muscle cells, which is known to be involved in intimal hyperplasia that accompanies atherosclerosis and post-angioplasty ... -
Mechanisms of salivary gland cell proliferation in vitro by P2Y2R activation
(University of Missouri--Columbia, 2012)Sjögren's syndrome (SS) and the side-effects of γ-radiation therapies for head and neck cancers cause salivary gland dysfunction. Salivary gland regeneration has been considered to be a very promising approach for restoring ... -
Neuroprotective roles of the P2Y[subscript 2] nucleotide receptor
(University of Missouri--Columbia, 2014)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Alzheimer's disease (AD) is the most prevalent neurodegenerative disease. AD is an important disease to study because of the high cost of care for ... -
Phenotypic modulation of vascular smooth muscle cells : evidence for a role of the G protein-coupled P2y2 receptor
(University of Missouri--Columbia, 2008)G protein-coupled receptors regulate two major functions of vascular smooth muscle cells (SMCs) - the vasomotor contractile response and the proliferative response. The contractile phenotype of SMCs has mainly been studied ... -
Role of P2Y₂ nucleotide receptors in reactive astrogliosis
(University of Missouri--Columbia, 2005)Astrocytes become activated in response to brain injury characterized by increased expression of GFAP and increased rates of cell migration and proliferation. Damage to brain cells causes the release of cytoplasmic ...