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    • University of Missouri-Columbia
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    • Clinical Inquiries (MU)
    • Clinical Inquiries, 2009
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    What does the evidence tell us about treating very-high-risk patients to an LDL <70 mg/dL?

    Nelson, Carrie
    Hitchcock, Kristin
    Bohlen, James A.
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    [PDF] WhatEvidenceTreatingLDL.pdf (125.8Kb)
    Date
    2009
    Format
    Article
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    Abstract
    No studies directly compare low-density lipoprotein (LDL) levels <70 mg/dL to levels of 71 to 100 mg/dL in very-high-risk patients. However, no evidence suggests a "floor" for LDL cholesterol levels beyond which further reductions of heart disease risk can't be achieved (strength of recommendation [SOR]: A, systematic reviews of randomized controlled trials [RCTs]). The target LDL cholesterol of <70 mg/dL is based on data extrapolated from RCTs (SOR: B).
    URI
    http://hdl.handle.net/10355/4005
    Part of
    Journal of family practice, 58, no. 12 (December 2009): 665-667.
    Rights
    OpenAccess.
    This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License.
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