What does the evidence tell us about treating very-high-risk patients to an LDL <70 mg/dL?

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What does the evidence tell us about treating very-high-risk patients to an LDL <70 mg/dL?

Please use this identifier to cite or link to this item: http://hdl.handle.net/10355/4005

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Title: What does the evidence tell us about treating very-high-risk patients to an LDL <70 mg/dL?
Author: Nelson, Carrie; Hitchcock, Kristin; Bohlen, James A.
Keywords: coronary artery disease
statin therapy
cholesterol
Date: 2009-12
Publisher: Family Physicians Inquiries Network
Citation: Journal of Family Practice, 58(12) 2009: 665-667.
Abstract: No studies directly compare low-density lipoprotein (LDL) levels <70 mg/dL to levels of 71 to 100 mg/dL in very-high-risk patients. However, no evidence suggests a “floor” for LDL cholesterol levels beyond which further reductions of heart disease risk can't be achieved (strength of recommendation [SOR]: A, systematic reviews of randomized controlled trials [RCTs]). The target LDL cholesterol of <70 mg/dL is based on data extrapolated from RCTs (SOR: B).
URI: http://hdl.handle.net/10355/4005

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