What does the evidence tell us about treating very-high-risk patients to an LDL <70 mg/dL?
Metadata[+] Show full item record
No studies directly compare low-density lipoprotein (LDL) levels <70 mg/dL to levels of 71 to 100 mg/dL in very-high-risk patients. However, no evidence suggests a “floor” for LDL cholesterol levels beyond which further reductions of heart disease risk can't be achieved (strength of recommendation [SOR]: A, systematic reviews of randomized controlled trials [RCTs]). The target LDL cholesterol of <70 mg/dL is based on data extrapolated from RCTs (SOR: B).
Journal of Family Practice, 58(12) 2009: 665-667.
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License.