Aspirin Use in Children for Fever or Viral Syndromes
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Aspirin should not be used to treat acute febrile viral illness in children. (Strength of Recommendation [SOR]: C, based on case- control studies). Although no causal link has been proven, data from case-control and historic cohort studies demonstrate an association between aspirin use and Reye syndrome.
American Family Physician, 80(12) 2009.