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dc.contributor.advisorSolbrekken, Gary Lawrenceeng
dc.contributor.authorMakarewicz, Philip Franklineng
dc.date.issued2013eng
dc.date.submitted2013 Summereng
dc.descriptionJuly 2013.eng
dc.descriptionA Thesis presented to the Faculty of the Graduate School at the University of Missouri--Columbia In Partial Fulfillment of the Requirements for the Degree Master of Science.eng
dc.descriptionThesis supervisor: Dr. Gary Solbrekken.eng
dc.description.abstractAs the nuclear community adapts to meet a constantly changing environment driven by policy development, so must the technology associated; in particular is the case of technology qualification. While government institutions and industry leaders have done much for the progression of nuclear materials, associated technologies must first be tested and qualified before they will see any practical use. Technetium-99m (99mTc) is a diagnostic radiopharmaceutical that is currently used about 100,000 times daily for diagnostic imaging procedures globally. The parent isotope for 99mTc is molybdenum-99 (99Mo), most commonly obtained through the irradiation of high enriched uranium (HEU). In accordance with the Department of Energy's Global Threat Reduction Initiative, an effort is underway to develop a process to produce 99Mo using low enriched uranium (LEU). One method utilizes LEU cast in the form of a metal foil as opposed to current powder based dispersion designs for HEU. New high-volume production LEU target concepts need to be analyzed to assure safe, reliable operation during all stages of production as use of a foil requires a significant modification to the current target design. The purpose of this research was to develop a set of experimental tools to assist in the qualification of target designs capable of economically producing 99Mo using LEU. These experimental tools could then be used in the verification of numerical analysis and results through various thermal, mechanical, and hydraulic testing. Methods included manufacturing target surrogates of different geometries. Heating loads and hydraulic flow-loops simulated the target in a reactor and testing measurements were used to quantify thermal resistance. Post evaluation of the target surrogates was also performed to compare testing results to theoretical values. Testing trends were compared to numerical and analytic models. A path forward is discussed in terms of the refinement of, and addition of new, qualification tools/techniques.eng
dc.description.bibrefIncludes bibliographical references (pages 120-123).eng
dc.format.extent1 online resource (x, 129 pages) : illustrations (some color)eng
dc.identifier.oclc897367319eng
dc.identifier.urihttps://hdl.handle.net/10355/40190
dc.identifier.urihttps://doi.org/10.32469/10355/40190eng
dc.languageEnglisheng
dc.publisherUniversity of Missouri--Columbiaeng
dc.relation.ispartofcollectionUniversity of Missouri--Columbia. Graduate School. Theses and Dissertationseng
dc.source.originalSubmitted by the University of Missouri--Columbia Graduate Schooleng
dc.subject.lcshRadiopharmaceuticals -- Utilizationeng
dc.subject.lcshTechnetium -- Isotopeseng
dc.subject.lcshMolybdenum -- Economic aspectseng
dc.subject.lcshNuclear medicineeng
dc.titleThermal mehcanical hydraulic experimental tools for molybdenum-99 production target analysiseng
dc.title.alternativeThermal/mechanical/hydraulic experimental tools for molybdenum-99 production target analysiseng
dc.typeThesiseng
thesis.degree.disciplineMechanical and aerospace engineering (MU)eng
thesis.degree.grantorUniversity of Missouri--Columbiaeng
thesis.degree.levelMasterseng
thesis.degree.nameM.S.eng


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