• Sphingolipid metabolic enzymes modulate anticancer drug resistance 

    Min, Junxia (University of Missouri--Columbia, 2006)
    Resistance to anticancer drugs is still a big obstacle for effective chemotherapy.To understand the underlying mechanisms, we generated sphingosine-1-phosphate (S-1-P)lyase (SPL) and sphingosine kinase (SK) mutants. Our ...