• SIRT1 deacetylation regulates NFAT transcriptional activity 

    Shannon, Stephen G., 1975- (University of Missouri--Columbia, 2009)
    [ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] The class III histone deacetylase SIRT1 plays important roles in aging, metabolism and biological clock control. We have recently demonstrated that ...
  • A study of readthrough therapy for spinal muscular atrophy in a transgenic mouse model 

    Terryberry, Melissa S. (University of Missouri--Columbia, 2009)
    [ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Spinal Muscular Atrophy (SMA) is due to the loss of the telomeric survival motor neuron gene (SMN1) and results in degeneration of motor neurons, muscle ...