Browsing 2007 MU dissertations - Freely available online by Thesis Advisor "Lever, Susan Z., 1952-"
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The effects of structural modifications on sigma receptor binding
(University of Missouri--Columbia, 2007)The sigma receptor is a unique receptor family that has two subtypes: sigma1 and sigma2. Sigma1 receptors are involved in several physiological functions such as psychosis and depression. Sigma2 receptors are expressed in ... -
Synthesis and structure-activity relationship of a series of sigma receptor ligands
(University of Missouri--Columbia, 2007)Sigma receptors are involved in several biological processes, and sigma ligands might be promising as cancer treatment agents, cocaine abuse medicines, and valuable psychiatric drugs. In an attempt to elucidate effectual ...