Do vitamins prevent or slow cognitive decline in Alzheimer disease?
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Do vitamins prevent or slow cognitive decline in Alzheimer disease? Evidence-Based Answer: A combination of B12, folate, and vitamin B6 may slow the decline of cognitive function in elderly patients with elevated homocysteine levels (>11–13 micromol/L), and a combination of B12 and folate may improve cognitive function in elderly patients with depression (SOR: B, single RCTs). However, the National Institutes of Health (NIH) does not recommend vitamins as a treatment for cognitive decline (SOR: C, expert opinion).
Evidence Based Practice 16(11): 11