Does vitamin D deficiency affect pregnancy outcomes?
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Does vitamin D deficiency affect pregnancy outcomes? Evidence-Based Answer: Routine vitamin D supplementation does not alter pregnancy outcomes (SOR: A, meta-analysis). However, vitamin D deficiency (serum level <20 ng/mL) during the late second trimester is associated with an increased risk of cesarean delivery, preeclampsia, and preterm delivery (SOR: B, observational studies). Pregnant patients with an identified deficiency may be treated (SOR: C, expert opinion), but the effect of replacement on pregnancy outcomes is unknown.
Evidence Based Practice 16(10): E-13-E-14